San Antonio Spurs vs. Cleveland Cavaliers Prediction & Odds | March 27, 2025

The San Antonio Spurs (31-40) will travel to Rocket Mortgage Fieldhouse to face the Cleveland Cavaliers (58-14). The 239 OU forecasts an offensive shootout even though Cleveland’s Evan Mobley is out (rest), Ty Jerome is questionable, and San Antonio’s De’Aaron Fox and Victor Wembanyama are on the shelf until next season.

The Cavs’ voluptuous -14.5 point spread is a hefty one, screaming Cleveland takes care of business. The Mobley injury opens up opportunities for De’Andre Hunter and Dean Wade while bumping Jarrett Allen’s usage/production. Most importantly, it leaves the Cavaliers with a hole defensively. Let’s look for some practical predictions based on the trends.

San Antonio Spurs vs. Cleveland Cavaliers Odds

San Antonio Spurs vs. Cleveland Cavaliers Match Details

• Fixture: San Antonio Spurs vs. Cleveland Cavaliers
• Date and Time: 3/27/25 6:10 pm CT
• Location: Rocket Arena, Cleveland, OH 

Key Stats

San Antonio Spurs 

Of the last five games, the Spurs have covered the spread in three, albeit only one of those was a playoff team (New York Knicks). These are the team’s only games with neither Fox nor Wembanyama. The injury bug did not bite their depth pieces like their stars: they are playing a 9 – 12 man rotation consistently, and there’s no indication this will change Thursday night. 

Without a blowout, the Spurs should run their top 10 players. This rotation bumps their scoring up and creates an opportunity to lean toward the team over. Evan Mobley is in second place for Defensive Player of the Year on FanDuel’s Sportsbook. Losing him would change the Cavs’ team defensively, especially from a rim-protecting standpoint. The Spurs can attack this even with limited firepower from their forwards/centers. 

Spurs last five games without De’Aaron Fox/Victor Wembanyama

ATS: 3 – 2 

Over 112.5 points: 3 – 2 

Cleveland Cavaliers

Over the last five games without Mobley, the Cavaliers have covered the spread only twice. More interestingly, they lost the other three outright and were double-digit favorites in each of those losses. Cleveland is the one seed in the Eastern Conference. The Celtics are five games back and on a seven-game winning streak, but the likelihood of them overtaking Cleveland as the one seed is hovering around 1%. This game means nothing to the Cavaliers in terms of seeding. 

The lack of seeding concern leads us to question Ty Jerome’s availability. He has proved his contribution in the games without Darius Garland and Donovan Mitchell. He secured the backup point guard role, allowing the Caves to trade Caris LeVert at the deadline for forward depth à la De’Andre Hunter. Even if he does play, it does not seem likely the Cavaliers would push him. Cavaliers’ last five games without Evan Mobley: 

ATS: 2 – 3 

Over 126.5 points: 2 – 3

Practical Predictions

The Spurs should keep this close thanks to the Mobley injury and offensive depth. Based on our data/model, the Spurs should keep this close enough to give us an edge. Final score: Cavs 122 – Spurs 118. This lets us take the Spurs, Spurs over and Cavs team under.

Final Pick

1. SPURS +14.5 (1.1 units) 
2. CAVALIERS Team Total Under 126 Points (1 Unit)  
3. SPURS Team Total Over 111 Points (1 Unit)